Water by coulometric Karl Fischer titration with oven

Quantitative determination of water content of bulk materials, lyophilisates or other solid test materials with low water but unknown or (potentially) interfering sample matrix and/or poor solubility in usual solvents

Therapeutic Modalities:

Biologics, Small Molecules

Development Phases:

Preclinical, Early-phase Clinical, Late-Phase Clinical, Commercial

Quality Standard:

GMP and non-GMP (ISO 9001:2015)

Pharmacopoeia:

Ph. Eur. general method 2.5.32, USP-NF general method <921>