Homogeneous asymmetric hydrogenation

Homogeneous asymmetric hydrogenation is the most powerful and versatile asymmetric catalytic transformation for the sustainable production of chiral active ingredients or intermediates thereof. This technology is considered mature and is currently applied on production scale up to multi 10,000 t/yr.

Solvias is a world leader in the field of asymmetric hydrogenation with an unparalleled track record. The combination of unbiased expertise, a world-class infrastructure (HTE platform) and an unmatched and versatile library of modular chiral catalysts and ligands is a key success factor when developing an asymmetric hydrogenation step.

Whether your hydrogenation substrate is rated ‘standard’, ‘challenging’ or ‘unprecedented’, Solvias assists you in finding the best catalyst, ligand and/or reaction conditions for your needs. Visit our Ligands & Catalysts Information Platform for detailed information on ligands and catalysts, catalytic applications and more.

Our service include:

  • Catalyst evaluation studies
  • Optimization of reaction conditions
  • Quality risk analysis
  • Production of up to multi kg amounts required for the various development phases (ISO or CGMP)
  • Catalyst separation studies
  • Support of Tech Transfer to designated CMO