C-C / C-X CROSS-COUPLING REACTIONS
Over the last two decades, the expanding field of Pd catalyzed C-C and C-X cross-coupling reactions has led to the development of numerous processes on a production scale. This powerful methodology is heavily used in both the life sciences and the fine chemicals industries.
Solvias assists you in catalyst evaluation and/or process optimization studies according to your requirements. The combination of catalysis expertise, an outstanding HTE platform and a state of the art library of ligands and isolated catalyst precursors for cross-coupling reactions allows an efficient development of your targeted transformation. Considering the large library of chiral ligands, Solvias is also capable to supporting you in the field of asymmetric cross-coupling and hydro-functionalization reactions. More detailed information can be found on our Ligands & Catalysts Information Platform.
Solvias’ area of expert services includes:
- Suzuki-Miyaura coupling
- Buchwald-Hartwig Amination (incl. direct amination in the presence of ammonia)
- Buchwald Amidation
- Sonogashira coupling
- Mizoroki-Heck coupling
- Negishi coupling
- Hydrofunctionalization reactions, such as hydroformylation, hydroalkoxylation, hydroamination, borylation