Biopharmaceutical Analysis

Amino acid analysis (AAA, Biochrom)
Analytical ultracentrifugation (AUC)

Calorimetry

Capillary electrophoresis (CE, various Beckmann and Agilent instruments, options for detection include UV absorbance with DAD, LIF and UV-CCD capillary imaging)

Capillary isoelectric focusing with capillary CCD imaging, jCE280)

Chromatography (All modes of LC, GC, many options of detectors and hyphenation)

Circular dichroism (CD)
Combustion analysis (C, H, N, O, S, halogens, inorganic ash, residue on combustion)
C-terminal amino acid sequencing (by chemical degradation or mass spectrometry)

Differential scanning calorimetry (DSC)

Dissolution calorimetry
Disulphide bond determination (see peptide mapping)
DNA (residual analysis, see Threshold method)
Dynamic light scattering (DLS)

Edman sequencing

Electrophoresis (capillary or slab-gel formats)
Elemental analysis (see combustion analysis)
Endotoxin determination (LAL)
Enzyme linked immunosorbent assay (ELISA)
Extinction coefficient determination (for proteins based upon AAA)

Fluorescence spectroscopy
Fourier transform infrared spectroscopy (FTIR)

Glycan analysis (by CE, Dionex ion exchange or MALDI-TOF/TOF-MS)

Heavy metal analysis (see inorganic elemental mass spectrometry)
HPLC, (High Performance Liquid Chromatography), RP, NP, chiral, SEC, IEC; Detectors: UV, DAD, FLD, RI, ECD, ELSD, MALLS, MS 
Host cell proteins (by ELISA)

I
nfrared spectroscopy (see fourier transform infrared spectroscopy)
Inorganic elemental mass spectrometry (ICP-MS)
Ion chromatography (Dionex HPAEC with PAD, see chromatography)
Iontrap mass spectrometry (ESI-MSn, hyphenated with LC)
Isoelectric focussing (capillary or slab-gel formats)
Isothermal titration calorimetry (ITC)

Karl-Fischer water determination (Special equipment to determine water content in lyophilisates and ampoules)
Kjeldahl nitrogen determination

LAL testing (endotoxins)
Liquid chromatography

Mass spectrometry (several modes, ESI-MSn, MALDI-TOF/TOF MS, ICP-MS)

Matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF/TOF MS, Bruker AutoFlex III)

Micro analytical combustion methods (see combustion analysis)

Monosaccharide analysis (CE or HPLC methods)
Multiangle light scattering, (MALS, miniDAWN®)

N-terminal amino acid sequencing (see Edman)
Nitrogen determination (see Kjeldahl)
Nuclear magnetic resonance spectroscopy (NMR)

Optical emission spectrometry (ICP-OES, fluorescence, phosphorescence)
Optical rotatory dispersion (ORD)
Osmolality
Osmolarity (freezing point depression)

Peptide mapping (LC-MS/MS for identification, LC-UV for quantification)
Pharmacopeial methods (USP, Pharm. Eur., BP, JP, Pharm. Helv.)
Physical measurements (density, viscosity, log P, pKa, conductivity, solubility, surface tension, refractive index, osmotic pressure, melting point, specific heat capacity)
Protein purification (LC, Äkta Purifier in refrigeration chamber)

Quantitative polymerase chain reaction (QPCR)

Raman spectroscopy

Real time PCR (see quantitative polymerase chain reaction)
Residue analysis (all molecular classes of impurity)
Robots (Biomek, Hydra, BioRobot)

Slab gel electrophoresis (SDS-PAGE, with visulisation using Coomassie brilliant bue, silver staining or western blotting)
Sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGEm, see slab gel electrophoresis)
Size exclusion chromatography (SEC)
Spectroscopy (IR, Raman, NMR, fluorescence, phosphorescence, UV/VIS, CD)
Surfactant analysis (e.g. Tween 80)

ThresholdTM method (molecular devices, for residual DNA)
Trace analysis
Tween 80 (by HPLC)

UV/VIS-spectroscopy

Water determination (see Karl Fischer)
Western blotting