Fluorination Chemistry

image: Services Fluorination Chemistry

Solvias has decades of experience in the synthesis of fluorinated intermediates and APIs. Our in-house database includes thousands of transformations performed in the field of fluorination chemistry. Our dedicated fluorination labs are equipped to handle any fluorination reagent safely, and with no corrosion problems, from g to kg scale. We master all the main chemoselective fluorination methods, using the complete range of fluorinating agents, for the synthesis of functionalized advanced intermediates. Some examples of fluorination reagents used include SF4, HF, F2, F-TEDA (SelectfluorTM) and NFSi. Reactions routinely performed are deoxo fluorination, Halex reaction, Schiemann reaction and electrophilic and nucleophilic fluorination.