Polymorphism, Salts, and Crystallization

Visual: Polymporphism, Salts, and Crystallization

Focusing on the best overall results for your drug candidate in terms of solid-state development, Solvias provides a comprehensive and integrated approach – from systematic salt, co-crystal, and polymorph screening to controlled scale-up of the crystallization process, complemented by a complete range of physico-chemical studies.

 

Method development for polymorphic purity and the optimization of crystallization processes supplements our services. We follow specifically designed strategies for a perfect fit with the development process. Our years of experience in the development of drugs help you crystallize your ideas.

 

Features and Key Success Factors

  • Integrated approach and proven study strategies
  • Flexible and modular procedure, with decision points throughout the programs
  • Effective communication within each project, with clear contact points
  • State-of-the-art technology and hyphenated techniques to explore the polymorph landscape and understand polymorphic transformations
  • Ability to handle highly potent and cytotoxic compounds
  • One of the biggest solid-state groups worldwide, with an outstanding track record

About Solid-State Development
An introduction to solid-state development
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Salt and Co-Crystals
For choosing the best solid form for development
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Polymorphic Purity and Amorphous Content    
Polymorph mixtures and amorphous content
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Single Parameters and Specialties
Material sciences support, from pre-clinical profiling to quality control
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Polymorphism Programs
Exploring the polymorph landscape and understanding polymorph transformations
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Crystallization
Crystallization screening and process development
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Intellectual Property and Consulting
Material sciences support for IP, testimonials and litigation
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