Confarma

C-C / C-X CROSS-COUPLING REACTIONS

Over the last two decades, the expanding field of Pd catalyzed C-C and C-X cross-coupling reactions has led to the development of numerous processes on a production scale. This powerful methodology is heavily used in both the life sciences and the fine chemicals industries.

Solvias assists you in catalyst evaluation and/or process optimization studies according to your requirements. The combination of catalysis expertise, an outstanding HTE platform and a state of the art library of ligands and isolated catalyst precursors for cross-coupling reactions allows an efficient development of your targeted transformation. Considering the large library of chiral ligands, Solvias is also capable to supporting you in the field of asymmetric cross-coupling and hydro-functionalization reactions. More detailed information can be found on our Ligands & Catalysts Information Platform.

Solvias’ area of expert services includes:

  • Suzuki-Miyaura coupling
  • Buchwald-Hartwig Amination (incl. direct amination in the presence of ammonia)
  • Buchwald Amidation
  • Sonogashira coupling
  • Mizoroki-Heck coupling
  • Negishi coupling
  • Carbonylation
  • Hydrofunctionalization reactions, such as hydroformylation, hydroalkoxylation, hydroamination, borylation