Confarma

Trouble-shooting particulate contamination

We can help you identify the root cause of foreign matter contamination in a fast, efficient and effective way. Solvias has a wealth of expertise in sophisticated particle isolation and preparation followed by light microscopy and either infrared (IR) spectroscopy or energy-dispersive x-ray (EDX) analysis.

Product contamination with unknown particles is a critical quality control issue. The affected production batch of an API may have to be discarded and production stopped, costing valuable time and money. We have state of the art equipment located at one unique site that supports our fast and structured approach to identify foreign particles using targeted iterative methods of analysis.

Our highly efficient troubleshooting capabilities allow us to employ a methodical approach that includes:

  1. isolate the particulate and prepare for analysis
  2. examine by light microscopy to define analytical method required
  3. analyse particles of inorganic origin by EDX in the scanning electron microscope (SEM)
  4. analyse particles of organic origin IR spectroscopy